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Eutylone and pentylone inhibited uptake at serotonin transporters (SERT), when dibutylone did not. Furthermore, eutylone and pentylone exhibited weak partial releasing actions at SERT which realized 50% of maximal response. All drugs stimulated dose-related locomotion in mice, and eutylone was most potent and efficacious in this regard (ED50 = 2 mg